SCHEMBL14833277 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK1	P28482	4/20	0.52

▸	FGFR3	P22607	13/20	0.41

▸	KDR	P35968	13/20	0.41

▸	FGFR1	P11362	12/20	0.41

▸	FGFR2	P21802	12/20	0.41

▸	FGFR4	P22455	11/20	0.41

▸	ILK	Q13418	1/20	0.40

▸	AKT1	P31749	1/20	0.40

▸	AKT2	P31751	1/20	0.40

▸	FLT3	P36888	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5211835	0.79	MAPK1 (0.59)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL29590784	0.79	MAPK1 (0.59)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL16642057	0.73	MAPK1 (0.52)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL28334784	0.73	DHODH (0.39)	MAPK1KDR
SCHEMBL12178898	0.73	TLR9 (0.55)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL2592957	0.73	MAPK1 (0.52)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL19749836	0.73	MAPK1 (0.52)	MAPK1FGFR3KDRFGFR1FGFR2
SCHEMBL5885621	0.71	TLR9 (0.53)	MAPK1KDRFLT3
SCHEMBL28334783	0.71	HPGD (0.51)	FGFR3KDR
SCHEMBL197153	0.70	AKT2 (0.61)	MAPK1ILKAKT1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013049701-A1	CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS	NEUPHARMA, INC. (US)	2013-04-04	—	—	WO	claimed