Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.86 |
| ▸ | F2 | P00734 | 9/20 | 0.64 |
| ▸ | KLK1 | P06870 | 5/20 | 0.64 |
| ▸ | F10 | P00742 | 3/20 | 0.64 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | F11 | P03951 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | CTRL | P40313 | 1/20 | 0.51 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.51 |
| ▸ | CTRC | Q99895 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20506164 | 0.92 | KLKB1 (1.00) | KLKB1F2KLK1F10PLG | |
| SCHEMBL14833789 | 0.91 | KLKB1 (0.81) | KLKB1F2KLK1F10PLG | |
| SCHEMBL14830240 | 0.91 | KLKB1 (1.00) | KLKB1F2KLK1F10PLG | |
| SCHEMBL20506477 | 0.85 | KLKB1 (1.00) | KLKB1F2KLK1F10PLG | |
| SCHEMBL20506234 | 0.85 | KLKB1 (0.73) | KLKB1F2KLK1F10PLG | |
| SCHEMBL14833813 | 0.85 | KLKB1 (0.84) | KLKB1F2KLK1F10PLG | |
| SCHEMBL20506340 | 0.85 | KLKB1 (1.00) | KLKB1F2KLK1F10PLG | |
| SCHEMBL14833271 | 0.85 | KLKB1 (0.73) | KLKB1F2KLK1F10PLG | |
| SCHEMBL20506221 | 0.85 | KLKB1 (0.83) | KLKB1F2KLK1F10PLG | |
| SCHEMBL20506410 | 0.85 | KLKB1 (0.73) | KLKB1F2KLK1F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049591-A2 | DUAL INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | VERSEON CORPORATION (US) | 2013-04-04 | — | — | WO | claimed |