Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 1.00 |
| ▸ | KLK1 | P06870 | 5/20 | 0.81 |
| ▸ | F2 | P00734 | 9/20 | 0.71 |
| ▸ | F10 | P00742 | 3/20 | 0.68 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | F11 | P03951 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CTRL | P40313 | 1/20 | 0.54 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20506221 | 0.91 | KLKB1 (0.83) | KLKB1KLK1F2F10PLG | |
| SCHEMBL14833262 | 0.90 | KLKB1 (1.00) | KLKB1KLK1F2F10 | |
| SCHEMBL14833813 | 0.90 | KLKB1 (0.84) | KLKB1KLK1F2F10PLG | |
| SCHEMBL14833789 | 0.88 | KLKB1 (0.81) | KLKB1KLK1F2F10PLG | |
| SCHEMBL20506164 | 0.87 | KLKB1 (1.00) | KLKB1KLK1F2F10PLG | |
| SCHEMBL14833324 | 0.87 | KLKB1 (0.81) | KLKB1KLK1F2F10PLG | |
| SCHEMBL20506097 | 0.87 | KLKB1 (0.95) | KLKB1KLK1F2F10PLG | |
| SCHEMBL14833254 | 0.86 | KLKB1 (0.75) | KLKB1KLK1F2F10PLG | |
| SCHEMBL20506340 | 0.86 | KLKB1 (1.00) | KLKB1KLK1F2F10PLG | |
| SCHEMBL14833305 | 0.86 | F2 (0.83) | KLKB1KLK1F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421036-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORP (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3421036-A1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | Verseon Corporation (US) | 2019-01-02 | — | — | EP | disclosed |
| EP-2968297-B1 | MULTISUBSTITUTED AROMATIC COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON CORP (US) | 2018-09-26 | — | — | EP | disclosed |