Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.83 |
| ▸ | KLKB1 | P03952 | 13/20 | 0.75 |
| ▸ | KLK1 | P06870 | 2/20 | 0.62 |
| ▸ | F10 | P00742 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20506477 | 0.86 | KLKB1 (1.00) | F2KLKB1KLK1F10 | |
| SCHEMBL20506221 | 0.77 | KLKB1 (0.83) | F2KLKB1KLK1F10 | |
| SCHEMBL12282625 | 0.77 | KLKB1 (1.00) | F2KLKB1KLK1F10MAPT | |
| SCHEMBL20506395 | 0.76 | KLKB1 (1.00) | F2KLKB1KLK1F10MAPT | |
| SCHEMBL14833813 | 0.75 | KLKB1 (0.84) | F2KLKB1KLK1F10 | |
| SCHEMBL14833262 | 0.75 | KLKB1 (1.00) | F2KLKB1KLK1F10 | |
| SCHEMBL14833188 | 0.75 | F2 (0.81) | F2KLKB1KLK1F10MAPT | |
| SCHEMBL14833480 | 0.74 | KLKB1 (1.00) | F2KLKB1KLK1F10MAPT | |
| SCHEMBL14706239 | 0.74 | KLKB1 (1.00) | F2KLKB1KLK1F10MAPT | |
| SCHEMBL14833254 | 0.74 | KLKB1 (0.75) | F2KLKB1KLK1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013049591-A2 | DUAL INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | VERSEON CORPORATION (US) | 2013-04-04 | — | — | WO | claimed |
| WO-2013049591-A2 | DUAL INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | VERSEON CORPORATION (US) | 2013-04-04 | — | — | WO | disclosed |