SCHEMBL148345

SCHEMBL148345

CN(C)C(=O)Nc1ccc(Br)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.68
KMT2A Q03164 2/20 0.68
TDP1 Q9NUW8 1/20 0.68
TSHR P16473 1/20 0.66
CA12 O43570 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA9 Q16790 1/20 0.58
APEX1 P27695 1/20 0.55
MAOA P21397 1/20 0.52
MAOB P27338 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8541703 1.00 MEN1 (0.68) MEN1KMT2ATDP1TSHRCA12
Hydrochloric Acid SCHEMBL20357592 0.98 MEN1 (0.66) MEN1KMT2ATDP1TSHRCA12
SCHEMBL687878 0.89 TSHR (0.79) MEN1KMT2ATDP1TSHRCA12
SCHEMBL11179381 0.85 MEN1 (0.60) MEN1KMT2ATDP1TSHRMAOA
SCHEMBL10942125 0.82 MEN1 (0.62) MEN1KMT2ATDP1TSHRMAOA
Metobromuron SCHEMBL8536617 0.81 KMT2A (1.00) MEN1KMT2ATDP1TSHRMAOA
SCHEMBL11757900 0.81 MEN1 (0.60) MEN1KMT2ATDP1TSHR
Metobromuron SCHEMBL53871 0.81 KMT2A (1.00) MEN1KMT2ATDP1TSHRMAOA
SCHEMBL8428436 0.81 TSHR (0.68) MEN1KMT2ATSHRCA12CA1
SCHEMBL4770587 0.81 TSHR (0.68) TDP1TSHRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2069 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119744118-A Herbicidal composition 拜耳公司 2025-04-01 CN claimed
CN-119709797-A Broad-spectrum amidase gene aphA for degrading amidol antibiotics and amidic herbicides, and encoding protein and application thereof 南京农业大学 2025-03-28 CN claimed
CN-118804684-A High load suspension concentrate compositions 安道麦阿甘有限公司 2024-10-18 CN claimed
CN-116272880-B Ureido functional group modified magnetic nanoparticle as well as preparation method and application thereof 中国检验检疫科学研究院 2024-08-30 CN claimed
US-20240130368-A1 HERBICIDAL COMPOSITION NIPPON SODA CO., LTD. (JP) 2024-04-25 US claimed
EP-4316244-A1 HERBICIDAL COMPOSITION Nippon Soda Co., Ltd. (JP) 2024-02-07 EP claimed
CN-116867373-A Herbicidal composition 日本曹达株式会社 2023-10-10 CN claimed
CN-116272880-A Ureido functional group modified magnetic nanoparticle as well as preparation method and application thereof 中国检验检疫科学研究院 2023-06-23 CN claimed
CN-114814013-B Method for rapidly screening unknown chemical hazard residues in aquatic products based on high-resolution mass spectrum database 中国海洋大学 2023-06-02 CN claimed
CN-112955011-B Compositions comprising pyridine carboxylic acid herbicides with photosystem II and optionally HPPD inhibitor herbicides 科迪华农业科技有限责任公司 2023-06-02 CN claimed
CN-110759978-A Mutant PSII D1 or psbA D1 protein, nucleic acid encoding same and application thereof 青岛清原化合物有限公司 2020-02-07 CN claimed
WO-2019115511-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-06-20 WO claimed
CN-106008276-A Synthesis method of phenylurea herbicide or deuteration-labeled phenylurea herbicide 湖北出入境检验检疫局检验检疫技术中心 2016-10-12 CN claimed
US-20140208463-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING SPECIFIC TETRAMIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-07-24 US claimed
CN-103717076-A Active compound combinations comprising specific tetramic acid derivatives BAYER IP GMBH 2014-04-09 CN claimed
WO-2013020985-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING SPECIFIC TETRAMIC ACID DERIVATIVES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-02-14 WO claimed
WO-2012076699-A1 BIOCIDE MICROCAPSULE FORMULATIONS CONTAINING STABILISED IODINE-CONTAINING COMPOUNDS LANXESS DEUTSCHLAND GMBH (DE) 2012-06-14 WO claimed
EP-2164323-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE Rohm and Haas Company (US) 2010-03-24 EP claimed
WO-2008071714-A1 MIXTURES COMPRISING 1-METHYLCYCLOPROPENE ROHM AND HAAS COMPANY (US) 2008-06-19 WO claimed
WO-2003000058-A1 SELECTIVE HERBICIDES BASED ON PYRIMIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2003-01-03 WO claimed