Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 9/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15551279 | 0.86 | CYP17A1 (0.45) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL14836039 | 0.83 | CYP17A1 (0.58) | CYP19A1CYP17A1IDO1CYP11B1CYP11B2 | |
| SCHEMBL14836126 | 0.82 | CYP17A1 (0.59) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9784386 | 0.78 | CYP17A1 (0.60) | CYP19A1CYP17A1IDO1CYP11B1ADRA2C | |
| SCHEMBL27912068 | 0.76 | CYP19A1 (0.45) | CYP19A1CYP17A1IDO1CYP11B1CYP11B2 | |
| SCHEMBL14876867 | 0.75 | CYP26A1 (0.39) | CYP19A1CYP17A1 | |
| SCHEMBL14837689 | 0.74 | CYP17A1 (0.48) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9661787 | 0.74 | IDO1 (0.41) | CYP19A1CYP17A1IDO1CYP11B1ADRA2C | |
| SCHEMBL14835851 | 0.70 | KDM4E (0.41) | CYP19A1CYP17A1 | |
| SCHEMBL14835769 | 0.69 | RAB9A (0.50) | CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014093960-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE | ANGION BIOMEDICA CORP. (US) | 2014-06-19 | — | — | WO | claimed |
| WO-2014015137-A2 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | ANGION BIOMEDICA CORP. (US) | 2014-01-23 | — | — | WO | claimed |
| EP-2576544-A2 | CYTOCHROME P450 INHIBITORS AND USES THEREOF | Angion Biomedica Corp. (US) | 2013-04-10 | — | — | EP | claimed |
| WO-2011153192-A2 | CYTOCHROME P450 INHIBITORS AND USES THEREOF | ANGION BIOMEDICA CORP. (US) | 2011-12-08 | — | — | WO | claimed |
| WO-2014093960-A1 | COMPOSITIONS AND METHODS FOR TREATING DISEASE | ANGION BIOMEDICA CORP. (US) | 2014-06-19 | — | — | WO | disclosed |
| WO-2014015137-A2 | COMPOSITIONS AND METHODS FOR TREATING DYSPROLIFERATIVE DISEASES | ANGION BIOMEDICA CORP. (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2576544-A2 | CYTOCHROME P450 INHIBITORS AND USES THEREOF | Angion Biomedica Corp. (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011153192-A2 | CYTOCHROME P450 INHIBITORS AND USES THEREOF | ANGION BIOMEDICA CORP. (US) | 2011-12-08 | — | — | WO | disclosed |