Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3211071 | 0.84 | BTK (0.69) | BTK | |
| SCHEMBL14837477 | 0.79 | BTK (0.51) | BTK | |
| SCHEMBL14837437 | 0.68 | BTK (0.44) | BTK | |
| SCHEMBL1726330 | 0.67 | BTK (0.85) | BTK | |
| SCHEMBL3207651 | 0.67 | BTK (0.69) | BTK | |
| SCHEMBL3673714 | 0.66 | BTK (0.79) | BTK | |
| SCHEMBL1725222 | 0.66 | BTK (1.00) | BTK | |
| SCHEMBL3207086 | 0.66 | BTK (0.81) | BTK | |
| SCHEMBL3143178 | 0.66 | BTK (0.49) | BTK | |
| SCHEMBL1725376 | 0.66 | BTK (0.86) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242749-B1 | NOVEL PYRIDINONES AND PYRIDAZINONES | HOFFMANN LA ROCHE (CH) | 2013-04-10 | — | — | EP | disclosed |