Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14800491 | 0.88 | P2RX3 (0.40) | P2RX3 | |
| SCHEMBL14800247 | 0.83 | P2RX3 (0.37) | P2RX3 | |
| SCHEMBL14800249 | 0.83 | P2RX3 (0.37) | P2RX3 | |
| SCHEMBL14800145 | 0.80 | P2RX3 (0.41) | P2RX3 | |
| SCHEMBL14800394 | 0.73 | CDK4 (0.37) | — | |
| SCHEMBL14800393 | 0.73 | CDK4 (0.37) | — | |
| SCHEMBL14800966 | 0.70 | NPC1 (0.40) | — | |
| SCHEMBL14816286 | 0.68 | PDE4B (0.31) | P2RX3 | |
| SCHEMBL14816285 | 0.68 | PDE4B (0.31) | P2RX3 | |
| SCHEMBL14800451 | 0.67 | KDR (0.45) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760843-A2 | SELECTIVE NR2B ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2013048949-A2 | SELECTIVE NR2B ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |