Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 9/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11160181 | 0.80 | OXTR (0.53) | OXTRAVPR1AMEN1KMT2AHDAC3 | |
| SCHEMBL334445 | 0.78 | MEN1 (0.50) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL10702229 | 0.74 | TSHR (0.66) | OXTRAVPR1AMEN1KMT2AHDAC1 | |
| SCHEMBL14838645 | 0.74 | HDAC3 (0.41) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL14830296 | 0.71 | HDAC4 (0.39) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL10705618 | 0.71 | MEN1 (0.43) | OXTRAVPR1AMEN1KMT2ATDP1 | |
| SCHEMBL1934549 | 0.71 | OXTR (0.53) | OXTRAVPR1AHDAC1HDAC6OPRM1 | |
| SCHEMBL10705013 | 0.70 | MEN1 (0.46) | OXTRAVPR1AMEN1KMT2A | |
| SCHEMBL11168777 | 0.69 | MEN1 (0.58) | OXTRAVPR1AMEN1KMT2AOPRM1 | |
| SCHEMBL17375904 | 0.69 | HDAC3 (0.50) | OXTRAVPR1AMEN1KMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013046211-A1 | PROCESSES FOR THE PREPARATION OF 5-CHLORO-N-({(5S)-2-OXO-3-[4-(3-OXO-4-MORPHOLINYL) PHENYL]-1,3-OXAZOLIDIN-5-YL}METHYL)-2-THIOPHENE-CARBOXAMIDE AND INTERMEDIATES THEREOF | SYMED LABS LIMITED (IN) | 2013-04-04 | — | — | WO | disclosed |