Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13962122 | 1.00 | PRKCA (0.51) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL12974362 | 1.00 | PRKCA (0.51) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL9894576 | 0.98 | PRKCA (0.49) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL2623191 | 0.95 | PRKCA (0.58) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL27496476 | 0.95 | PRKCA (0.58) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL5945204 | 0.95 | PRKCA (0.58) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL10071408 | 0.95 | PRKCA (0.58) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL15035699 | 0.94 | PRKCA (0.47) | PRKCADGKATSHRPAMPRKCD | |
| SCHEMBL16425186 | 0.94 | PRKCA (0.50) | PRKCADGKATSHRPRKCDKDM4E | |
| SCHEMBL10071406 | 0.93 | PRKCA (0.56) | PRKCADGKATSHRPAMPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152543-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-09-25 | — | — | WO | disclosed |
| US-20140264165-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140264165-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL CORPORATION (US) | 2014-09-18 | — | — | US | disclosed |
| US-20140209951-A1 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | Henkel IP & Holding GmbH (DE) | 2014-07-31 | — | — | US | disclosed |
| WO-2013049154-A2 | OXETANE-CONTAINING COMPOUNDS AND COMPOSITIONS THEREOF | HENKEL AG & CO. KGAA (DE) | 2013-04-04 | — | — | WO | disclosed |