Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.66 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.66 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839488 | 1.00 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL2782203 | 0.93 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL29723157 | 0.93 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL14165062 | 0.93 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL15786231 | 0.93 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL13212480 | 0.93 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL15790650 | 0.89 | PDE4B (0.55) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL19673799 | 0.89 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL15790651 | 0.88 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DABCB11 | |
| SCHEMBL16802335 | 0.87 | PDE4B (0.49) | PDE4APDE4BPDE4CPDE4DABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928869-B1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |
| WO-2013045280-A1 | DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2013-04-04 | — | — | WO | disclosed |