Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 3/20 | 0.46 |
| ▸ | GABRD | O14764 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.46 |
| ▸ | GABRE | P78334 | 3/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL3932257 | 0.82 | GABRR1 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL19327226 | 0.81 | LMNA (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL692834 | 0.81 | — | — | |
| SCHEMBL16306471 | 0.81 | — | — | |
| SCHEMBL27881539 | 0.81 | — | — | |
| SCHEMBL28698292 | 0.81 | — | — | |
| SCHEMBL28373386 | 0.81 | — | — | |
| SCHEMBL36062 | 0.81 | — | — | |
| SCHEMBL1142305 | 0.79 | — | — | |
| Bromide SCHEMBL11687258 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650718-B2 | Electroless copper plating solution | ATOTECH DEUTSCHLAND GMBH (DE) | 2017-05-16 | — | — | US | disclosed |
| US-20160053379-A1 | ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH & CO. KG (F/K/A ATOTECH DEUTSCHLAND GMBH) (DE) | 2016-02-25 | — | — | US | disclosed |
| EP-2784181-B1 | Electroless copper plating solution | ATOTECH DEUTSCHLAND GMBH (DE) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014154689-A1 | ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-10-02 | — | — | WO | disclosed |
| EP-2784181-A1 | Electroless copper plating solution | ATOTECH Deutschland GmbH (DE) | 2014-10-01 | — | — | EP | disclosed |
| US-20140242264-A1 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-08-28 | — | — | US | disclosed |
| EP-2764135-A2 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTION | Atotech Deutschland GmbH (DE) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050332-A2 | FORMALDEHYDE-FREE ELECTROLESS COPPER PLATING SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2013-04-11 | — | — | WO | disclosed |