Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27962367 | 0.95 | ALOX5AP (0.39) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL14844552 | 0.93 | ALOX5AP (0.40) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL14844504 | 0.93 | ALOX5AP (0.40) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL14844339 | 0.88 | ALOX5AP (0.43) | ALOX5APFEN1ALDH1A1HPGDSCN9A | |
| SCHEMBL17510160 | 0.87 | ALOX5AP (0.37) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL23155073 | 0.85 | ALOX5AP (0.36) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL29968111 | 0.85 | ALOX5AP (0.36) | ALOX5APFEN1ALDH1A1HPGDABCB11 | |
| SCHEMBL14844537 | 0.83 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1SCN9ADDR1 | |
| SCHEMBL29464818 | 0.83 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1SCN9ADDR1 | |
| SCHEMBL14844547 | 0.82 | ALOX5AP (0.38) | ALOX5APFEN1ALDH1A1HPGDSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763968-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LTD (GB) | 2016-02-24 | — | — | EP | disclosed |
| EP-2763968-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | Syngenta Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013050421-A1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |