Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23155073 | 1.00 | ALOX5AP (0.36) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL27962367 | 0.88 | ALOX5AP (0.39) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL14844503 | 0.85 | ALOX5AP (0.41) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL14844339 | 0.83 | ALOX5AP (0.43) | ALOX5APFEN1ALDH1A1HPGDHTR2A | |
| SCHEMBL14844552 | 0.82 | ALOX5AP (0.40) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL14844504 | 0.82 | ALOX5AP (0.40) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL17510160 | 0.77 | ALOX5AP (0.37) | ALOX5APFEN1ABCB11ITGB1ITGA4 | |
| SCHEMBL29464818 | 0.77 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1PTGS2PDE2A | |
| SCHEMBL14844537 | 0.77 | ALOX5AP (0.44) | ALOX5APFEN1ALDH1A1PTGS2PDE2A | |
| SCHEMBL14844547 | 0.76 | ALOX5AP (0.38) | ALOX5APFEN1ALDH1A1HPGDPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220312767-A1 | PYRIDAZINE COMPOUNDS AND HERBICIDES | NIPPON SODA CO., LTD. (JP) | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220312767-A1 | PYRIDAZINE COMPOUNDS AND HERBICIDES | CBR3, CHRM2, CBR1 | ALOX5AP 2970/4885FEN1 3846/4885ABCB11 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.