Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 6/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 4/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978726 | 0.87 | PARP1 (0.41) | NCOA1NCOA3PARP1PARP10PARP11 | |
| SCHEMBL30401909 | 0.87 | PARP1 (0.41) | NCOA1NCOA3PARP1PARP10PARP11 | |
| SCHEMBL14854352 | 0.79 | DYRK1A (0.43) | NCOA1NCOA3PARP1PARP10F7 | |
| SCHEMBL3967795 | 0.78 | KDM4E (0.54) | KDM4EALDH1A1HPGDMAPTTUBB4A | |
| SCHEMBL14845163 | 0.76 | PARP1 (0.42) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL9741532 | 0.74 | KDM4E (0.61) | NCOA1NCOA3PARP1PARP10PARP11 | |
| SCHEMBL11184319 | 0.73 | PARP1 (0.45) | NCOA1NCOA3PARP1PARP10PARP11 | |
| SCHEMBL15814278 | 0.73 | NCOA1 (0.43) | NCOA1NCOA3PARP1PARP10PARP11 | |
| SCHEMBL4715588 | 0.71 | PARP10 (0.53) | PARP1PARP10PARP11F7F3 | |
| SCHEMBL30882012 | 0.71 | PARP10 (0.53) | PARP1PARP10PARP11F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763539-B1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LTD (GB) | 2017-02-08 | — | — | EP | disclosed |
| US-9340556-B2 | Antibacterial compounds | GLAXO GROUP LIMITED (GB) | 2016-05-17 | — | — | US | disclosed |
| CN-104039152-A | Antibacterial compounds | GLAXO GROUP LTD | 2014-09-10 | — | — | CN | disclosed |
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2014-09-04 | — | — | US | disclosed |
| EP-2763539-A1 | ANTIBACTERIAL COMPOUNDS | Glaxo Group Limited (GB) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013052568-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249126-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, PEPD, ABCB11 | NCOA1 3323/4885NCOA3 4362/4885PARP1 4430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.