Iodide

Iodide

SCHEMBL14844987

CC1=Nc2ccccc2C1(C)C.I

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MDM2 Q00987 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ADORA3 P0DMS8 1/20 0.33
HTR5A P47898 1/20 0.32
GAA P10253 1/20 0.32
PDK2 Q15119 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL27561391 1.00 CASP3 (0.46) CASP3RAB9AATMNPSR1SENP8
SCHEMBL101153 0.98 CASP3 (0.47) CASP3RAB9AATMNPSR1SENP8
Bromide SCHEMBL28640491 0.96 CASP3 (0.46) CASP3RAB9AATMNPSR1SENP8
Bromide SCHEMBL28264772 0.96 CASP3 (0.46) CASP3RAB9AATMNPSR1SENP8
Hydrochloric Acid SCHEMBL27775077 0.96 CASP3 (0.46) CASP3RAB9AATMNPSR1SENP8
SCHEMBL28208023 0.96 KDM4E (0.47) CASP3RAB9AATMNPSR1SENP8
Bromide SCHEMBL28631392 0.96 CASP3 (0.46) CASP3RAB9AATMNPSR1SENP8
SCHEMBL9193904 0.88 CASP3 (0.42) CASP3RAB9AATMNPSR1SENP8
Acetonitrile SCHEMBL28236935 0.88 CASP3 (0.42) CASP3RAB9AATMNPSR1SENP8
Sulfuric Acid SCHEMBL29286627 0.87 TDP1 (0.44) CASP3RAB9AATMNPSR1SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3148594-A1 PHOTOCHROMIC DETECTION OF ULTRAVIOLET IRRADIATION PURPLESUN INC. (US) 2017-04-05 EP disclosed
WO-2015184190-A1 PHOTOCHROMIC DETECTION OF ULTRAVIOLET IRRADIATION PURPLESUN INC. (US) 2015-12-03 WO disclosed
US-20150343102-A1 PHOTOCHROMIC DETECTION OF ULTRAVIOLET IRRADIATION PURPLESUN INC. 2015-12-03 US disclosed
WO-2013050431-A1 A SALT FOR COLOR FILTER APPLICATION, A PROCESS FOR MAKING THE SAME, AND A COLORANT COMPRISING THE SAME SOLVAY SA (BE) 2013-04-11 WO disclosed