Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | CES1 | P23141 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025145 | 1.00 | TSHR (0.58) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL11490166 | 1.00 | TSHR (0.58) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL2564553 | 1.00 | TSHR (0.58) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL14993129 | 1.00 | TSHR (0.58) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL9095301 | 0.98 | CES2 (0.57) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL9095382 | 0.93 | CES2 (0.56) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL16349103 | 0.91 | TDP1 (0.62) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL13875402 | 0.91 | TDP1 (0.62) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL14992716 | 0.88 | CES2 (0.50) | TSHRCES2CES1LMNAALDH1A1 | |
| SCHEMBL14992717 | 0.88 | CES2 (0.50) | TSHRCES2CES1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8414982-B2 | Process for the production of strongly adherent coatings | BASF SE (DE) | 2013-04-09 | — | — | US | disclosed |