Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10142401 | 1.00 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL10142407 | 0.93 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL10142790 | 0.92 | TMPRSS2 (0.30) | TMPRSS2 | |
| SCHEMBL10142778 | 0.90 | TMPRSS2 (0.34) | TMPRSS2 | |
| SCHEMBL10120250 | 0.90 | CYP3A4 (0.36) | TMPRSS2 | |
| SCHEMBL10142598 | 0.90 | CYP3A4 (0.36) | TMPRSS2 | |
| SCHEMBL14845682 | 0.89 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL22096270 | 0.88 | TMPRSS2 (0.44) | TMPRSS2 | |
| SCHEMBL17215150 | 0.86 | TMPRSS2 (0.33) | TMPRSS2 | |
| SCHEMBL22096276 | 0.85 | POLRMT (0.33) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8415308-B2 | 1′-substituted-carba-nucleoside prodrugs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-04-09 | — | — | US | disclosed |