Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.55 |
| ▸ | CTSK | P43235 | 6/20 | 0.55 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.49 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845880 | 0.97 | CTSS (0.54) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL145280 | 0.80 | EPHX1 (0.44) | KMT2AGAAALDH1A1LMNAMEN1 | |
| SCHEMBL1268688 | 0.80 | EPHX1 (0.44) | KMT2AGAAALDH1A1LMNAMEN1 | |
| SCHEMBL79825 | 0.80 | EPHX1 (0.44) | KMT2AGAAALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL2417195 | 0.79 | EPHX1 (0.43) | KMT2AALDH1A1LMNAMEN1 | |
| Hydrochloric Acid SCHEMBL2422106 | 0.79 | EPHX1 (0.43) | KMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL13961183 | 0.77 | HDAC4 (0.44) | CTSSCTSKCAPN1KMT2AGAA | |
| SCHEMBL27448658 | 0.76 | CA1 (0.41) | CTSSCTSKCTSLCTSBKMT2A | |
| SCHEMBL16528516 | 0.76 | EPHX1 (0.47) | CTSSCTSKGAALMNAHDAC4 | |
| SCHEMBL487705 | 0.76 | EPHX1 (0.47) | CTSSCTSKGAALMNAHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605296-B2 | Fluorogenic peptidase substrate | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-03-28 | — | — | US | disclosed |
| US-20140234887-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | CENTRE NATIONAL DE LA RECHERCHE SCIENTFIQUE (FR) | 2014-08-21 | — | — | US | disclosed |
| WO-2013045854-A1 | FLUOROGENIC PEPTIDASE SUBSTRATE | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2013-04-04 | — | — | WO | disclosed |