Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829352 | 0.95 | LIPG (0.80) | LIPGLIPC | |
| SCHEMBL14846238 | 0.89 | LIPG (0.91) | LIPGLIPC | |
| SCHEMBL14846262 | 0.89 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL14846203 | 0.89 | LIPG (0.80) | LIPGLIPC | |
| SCHEMBL14846287 | 0.89 | LIPG (0.81) | LIPGLIPC | |
| SCHEMBL14846224 | 0.88 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL17751153 | 0.88 | LIPG (0.77) | LIPGLIPC | |
| SCHEMBL14846283 | 0.88 | LIPG (0.89) | LIPGLIPC | |
| SCHEMBL14846221 | 0.88 | LIPG (0.90) | LIPGLIPC | |
| SCHEMBL14846670 | 0.88 | LIPG (0.80) | LIPGLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249096-B2 | Pyrrolinone carboxamide compounds useful as endothelial lipase inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| EP-2760828-B1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2013049096-A1 | PYRROLINONE CARBOXAMIDE COMPOUNDS USEFUL AS ENDOTHELIAL LIPASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | WO | disclosed |