Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6 | P05231 | 8/20 | 0.48 |
| ▸ | PGR | P06401 | 10/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17676709 | 0.91 | IL6 (0.51) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL2393561 | 0.90 | IL6 (0.53) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL447508 | 0.90 | IL6 (0.51) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL14847748 | 0.89 | IL6 (0.49) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL14847670 | 0.89 | IL6 (0.49) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL14847647 | 0.88 | IL6 (0.49) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL1314664 | 0.87 | IL6 (0.52) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL14847754 | 0.87 | IL6 (0.52) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL14847500 | 0.87 | IL6 (0.48) | IL6PGRNR3C1ARESR1 | |
| SCHEMBL4424483 | 0.87 | IL6 (0.51) | IL6PGRNR3C1ARESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2085387-B1 | NOVEL 1,2-DIHYDROQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER-INTRODUCED PHENYL GROUP AS SUBSTITUENTS | SANTEN PHARMACEUTICAL CO LTD (JP) | 2013-04-10 | — | — | EP | disclosed |