Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850825 | 1.00 | TACR3 (0.40) | TACR3 | |
| SCHEMBL3814982 | 0.74 | TACR3 (0.45) | TACR3 | |
| SCHEMBL930180 | 0.68 | TACR3 (0.54) | TACR3 | |
| SCHEMBL930821 | 0.68 | TACR3 (0.42) | TACR3 | |
| SCHEMBL29184116 | 0.66 | TACR3 (0.49) | TACR3 | |
| SCHEMBL929377 | 0.66 | TACR3 (0.49) | TACR3 | |
| SCHEMBL5231477 | 0.63 | TACR3 (0.46) | TACR3 | |
| SCHEMBL928185 | 0.61 | TACR3 (0.57) | TACR3 | |
| SCHEMBL14844512 | 0.60 | TACR3 (0.52) | TACR3 | |
| SCHEMBL930711 | 0.60 | TACR3 (0.59) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013050424-A1 | NOVEL CHIRAL N-ACYL-5,6,7,(8-SUBSTITUTED)-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR MEDIATED DISORDERS AND CHIRAL SYNTHESIS THEREOF | EUROSCREEN S.A. (BE) | 2013-04-11 | — | — | WO | disclosed |