Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930821 | 0.80 | TACR3 (0.42) | TACR3 | |
| SCHEMBL930180 | 0.74 | TACR3 (0.54) | TACR3 | |
| SCHEMBL14850736 | 0.74 | TACR3 (0.40) | TACR3 | |
| SCHEMBL14850825 | 0.74 | TACR3 (0.40) | TACR3 | |
| SCHEMBL929377 | 0.73 | TACR3 (0.49) | TACR3 | |
| SCHEMBL928185 | 0.67 | TACR3 (0.57) | TACR3 | |
| SCHEMBL5935866 | 0.66 | MGLL (0.43) | — | |
| SCHEMBL929542 | 0.66 | TACR3 (0.59) | TACR3 | |
| SCHEMBL1200543 | 0.65 | TACR3 (0.33) | TACR3 | |
| SCHEMBL3813368 | 0.65 | CDC42 (0.36) | TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2090576-A1 | 6-halo-pyrazolo[1,5-a]pyridines, a process for their preparation and their use as metabotropic glutamate receptor (mGluR) modulators | Merz Pharma GmbH & Co.KGaA (DE) | 2009-08-19 | — | — | EP | disclosed |