Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 1.00 |
| ▸ | PIK3C2G | O75747 | 5/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 4/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 2/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 0.73 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420845 | 1.00 | PIK3CD (1.00) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851892 | 0.93 | PIK3CD (0.87) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL24535575 | 0.93 | PIK3CD (0.86) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL22336531 | 0.92 | PIK3CD (0.85) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL24535456 | 0.91 | PIK3CD (0.84) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL22338311 | 0.90 | PIK3CD (0.82) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851607 | 0.90 | PIK3C2G (0.82) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851645 | 0.89 | PIK3C2G (0.81) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL14851641 | 0.89 | PIK3C2G (0.80) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB | |
| SCHEMBL22336535 | 0.89 | PIK3CD (0.80) | PIK3CDPIK3C2GPIK3CGPIK3CAPI4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-03-02 | — | — | US | disclosed |
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-23 | — | — | US | disclosed |
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2022-05-19 | — | — | US | disclosed |
| WO-2020163594-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163598-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-13 | — | — | WO | disclosed |
| US-9309236-B2 | PI-kinase inhibitors with broad spectrum anti-infective activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2015-02-19 | — | — | US | disclosed |
| WO-2013052845-A1 | PI-KINASE INHIBITORS WITH BROAD SPECTRUM ANTI-INFECTIVE ACTIVITY | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | CD74, CD2BP2, SERPINB1 | PIK3CD 3580/4885PIK3C2G 3600/4885PIK3CG 3212/4885 |
| US-20150051193-A1 | PI-kinase Inhibitors with Broad Spectrum Anti-Infective Activity | PIP4K2A, PIP5K1A, PIP4K2C | PIK3CD 20/4885PIK3C2G 89/4885PIK3CG 22/4885 |
| US-20230063768-A1 | IMMUNOPHILIN BINDING AGENTS AND USES THEREOF | PMP22, MAG, FABP7 | PIK3CD 4766/4885PIK3C2G 4504/4885PIK3CG 4534/4885 |
| US-20220153711-A1 | P14-Kinase Inhibitors and Methods of Using the Same | PI4KB, PI4KA, PI4K2A | PIK3CD 29/4885PIK3C2G 157/4885PIK3CG 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.