Lupeol

Lupeol

SCHEMBL148518

C=C(C)[C@@H]1CC[C@]2(C)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 1.00
TOP2A P11388 2/20 1.00
CES2 O00748 1/20 1.00
CES1 P23141 1/20 1.00
PTGES O14684 2/20 0.76
USP2 O75604 2/20 0.74
LMNA P02545 2/20 0.74
HIF1A Q16665 2/20 0.74
NT5E P21589 2/20 0.74
RELA Q04206 1/20 0.74
RORC P51449 5/20 0.72
ALB P02768 3/20 0.72
GPBAR1 Q8TDU6 2/20 0.72
AKR1B10 O60218 1/20 0.72
POLB P06746 1/20 0.72
GLI1 P08151 1/20 0.72
AKR1B1 P15121 1/20 0.72
DPP4 P27487 1/20 0.72
SAE1 Q9UBE0 1/20 0.72
UBA2 Q9UBT2 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lupeol SCHEMBL14067725 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL148519 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL18100186 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL17036708 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL10061311 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL561024 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL7742344 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL21927816 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL21847985 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL15263404 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5070 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144740-A1 COSMETIC ACTIVE INGREDIENT DERIVED FROM A NON-VOLATILE FRACTION OF CANARIUM EXUDATE AND USES THEREOF FLORE SCOLA (FR) 2026-05-28 US claimed
EP-3989943-B1 COMPOSITION COMPRISING AT LEAST ONE TRITERPENE AND/OR AT LEAST ONE TRITERPENOID AND/OR AT LEAST ONE OF THE GLYCOSYLATED FORMS THEREOF TILMAN (BE) 2026-05-20 EP claimed
CN-122056926-A Probiotic composition containing melatonin and application of composition in sleep 南京北极光生物科技有限公司 2026-05-19 CN claimed
CN-122005577-A Application of lupeol in preparation of medicine for preventing or treating kidney injury caused by cisplatin 重庆医科大学附属儿童医院 2026-05-12 CN claimed
CN-122028909-A Lipid nanoparticles with non-covalent bifunctional conjugates for active targeting 莫特治疗股份有限公司 2026-05-12 CN claimed
CN-122012485-A Isopentenyl diphosphate isomerase mutant, method for improving lupeol production of yarrowia lipolytica and application 皖西学院 2026-05-12 CN claimed
CN-122005588-A Pharmaceutical composition containing evodiaoside, drug carrying system and application thereof in osteoarthritis 江苏省中医药研究院(江苏省中西医结合医院) 2026-05-12 CN claimed
WO-2026088119-A1 LIPIDATED TLR7/8 MODULATORS AS ADJUVANTS AND USES THEREOF PFIZER INC. (US) 2026-04-30 WO claimed
US-20260115228-A1 Chimeric Antigen Receptors Targeting CD19 ORNA THERAPEUTICS, INC. (US) 2026-04-30 US claimed
US-20260115324-A1 Chimeric Antigen Receptors Targeting CD19 ORNA THERAPEUTICS, INC. (US) 2026-04-30 US claimed
EP-0476054-A4 METHOD FOR TREATING VIRAL INFECTION 1992-08-12 EP claimed
US-5126376-A Terpene ozonides WESTERN HOLDING COMPANY LIMITED (LI) 1992-06-30 US claimed
EP-0476054-A1 METHOD FOR TREATING VIRAL INFECTION HERMAN, Stephen (US) 1992-03-25 EP claimed
US-5086076-A For treating aids WESTERN HOLDING COMPANY LIMITED (LI) 1992-02-04 US claimed
EP-0427781-A4 OZONIDES OF TERPENES AND THEIR MEDICAL USES 1991-08-21 EP claimed
EP-0427781-A1 OZONIDES OF TERPENES AND THEIR MEDICAL USES HERMAN, Stephen (US) 1991-05-22 EP claimed
US-4983637-A PARENTERAL ADMINISTRATION OF OZONIDES OF TERPENES CLIVEDEN LTD. (BS) 1991-01-08 US claimed
WO-1990014764-A1 METHOD FOR TREATING VIRAL INFECTION HERMAN STEPHEN (US) 1990-12-13 WO claimed
WO-1989012626-A1 OZONIDES OF TERPENES AND THEIR MEDICAL USES HERMAN STEPHEN (US) 1989-12-28 WO claimed
US-4220588-A PREPARATION OF ALPHA, BETA-UNSATURATED ALDEHYDE OR KETONE BY DEHYOROGENATING WITH ARYLSELENINIC ANHYDRIDE RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC., 49 AMHERST ST., CAMBRIDGE, MA. 02142, 1980-09-02 US claimed