Lupeol

Lupeol

SCHEMBL561024

C=C(C)[C@@H]1CC[C@]2(C)CCC3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 5/20 1.00
TOP2A P11388 2/20 1.00
CES2 O00748 1/20 1.00
CES1 P23141 1/20 1.00
PTGES O14684 2/20 0.76
USP2 O75604 2/20 0.74
LMNA P02545 2/20 0.74
HIF1A Q16665 2/20 0.74
NT5E P21589 2/20 0.74
RELA Q04206 1/20 0.74
RORC P51449 5/20 0.72
ALB P02768 3/20 0.72
GPBAR1 Q8TDU6 2/20 0.72
AKR1B10 O60218 1/20 0.72
POLB P06746 1/20 0.72
GLI1 P08151 1/20 0.72
AKR1B1 P15121 1/20 0.72
DPP4 P27487 1/20 0.72
SAE1 Q9UBE0 1/20 0.72
UBA2 Q9UBT2 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lupeol SCHEMBL14067725 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL148519 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL18100186 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL17036708 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL10061311 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL7742344 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL148518 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL21927816 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL21847985 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES
Lupeol SCHEMBL15263404 1.00 PTPN1 (1.00) PTPN1TOP2ACES2CES1PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642471-A1 PLANT HYDROETHANOLIC EXTRACTS AND USES THEREOF IMMUNE & GENETICS PROTOCOLS LLC (US) 2025-11-05 EP disclosed
EP-4642472-A1 PLANT HYDROETHANOLIC EXTRACTS O SIGMA CELL AND GENETIC LLC (US) 2025-11-05 EP disclosed
EP-3600563-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING VITAMIN D3 AND HYALURONIC ACID JOYDERMA AG (CH) 2025-09-10 EP disclosed
CN-119198968-B Method for determining content of triterpene alcohol in camellia oil 杭州千岛湖天鑫有限公司 2025-03-25 CN disclosed
US-20250042765-A1 METHOD FOR TREATING A SURFACE CONTAMINATED WITH PSEUDOMONAS AERUGINOSA IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2025-02-06 US disclosed
US-12178900-B2 Pharmaceutical compositions JOYDERMA AG (CH) 2024-12-31 US disclosed
CN-119198968-A Method for determining content of triterpene alcohol in camellia oil 杭州千岛湖天鑫有限公司 2024-12-27 CN disclosed
US-12157677-B2 Method for treating a biologically contaminated surface IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) 2024-12-03 US disclosed
WO-2024141931-A1 PLANT HYDROETHANOLIC EXTRACTS O SIGMA CELL AND GENETIC LLC (US) 2024-07-04 WO disclosed
WO-2024141930-A1 PLANT HYDROETHANOLIC EXTRACTS AND USES THEREOF IMMUNE & GENETICS PROTOCOLS LLC (US) 2024-07-04 WO disclosed
US-8815305-B2 Composition containing a plant extract and process for producing same BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2014-08-26 US disclosed
CN-102770149-B Method and device for simultaneously producing ultra-high purity betulin and high purity betulinic acid from birch bark KOREA ENERGY RESEARCH INST 2014-05-14 CN disclosed
CN-102770149-A Method and device for simultaneously producing ultra-high purity betulin and high purity betulinic acid from birch bark KOREA ENERGY RESEARCH INST 2012-11-07 CN disclosed
EP-2514430-A2 METHOD AND APPARATUS FOR SIMULTANEOUSLY MANUFACTURING ULTRA PURE BETULIN AND HIGHLY PURE BETULINIC ACID FROM BIRCH BARK Korea Institute of Energy Research (KR) 2012-10-24 EP disclosed
US-20120035119-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss Alvia FZE (AE) 2012-02-09 US disclosed
WO-2011074766-A2 METHOD AND APPARATUS FOR SIMULTANEOUSLY MANUFACTURING ULTRA PURE BETULIN AND HIGHLY PURE BETULINIC ACID FROM BIRCH BARK 한국에너지기술연구원 (KR) 2011-06-23 WO disclosed
EP-1711194-B1 A PLANT EXTRACT AND ITS PHARMACEUTICAL AND COSMETIC USE COGNIS FRANCE SAS (FR) 2009-11-25 EP disclosed
US-20070281047-A1 Composition Containing a Plant Extract and Process for Producing Same COGNIS FRANCE, S.A.S. (FR) 2007-12-06 US disclosed
EP-1711194-A1 A PLANT EXTRACT AND ITS PHARMACEUTICAL AND COSMETIC USE Cognis France, S.A.S. (FR) 2006-10-18 EP disclosed
WO-2005039610-A1 A PLANT EXTRACT AND ITS PHARMACEUTICAL AND COSMETIC USE COGNIS FRANCE, S.A.S. (FR) 2005-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035119-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss SHH, TYR, CAT PTPN1 4394/4885TOP2A 2536/4885CES2 1803/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.