Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.74 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.74 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.43 |
| ▸ | CLK1 | P49759 | 3/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.43 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852096 | 0.85 | PIM1 (1.00) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852501 | 0.82 | PIM1 (0.93) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852269 | 0.82 | PIM1 (0.80) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852187 | 0.81 | PIM1 (0.79) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852046 | 0.81 | NEK2 (0.49) | PIM1PIM3PIM2PIK3CDNEK2 | |
| SCHEMBL14852130 | 0.80 | PIM1 (0.82) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852145 | 0.80 | PIM1 (0.65) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852447 | 0.79 | PIM1 (0.85) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852197 | 0.79 | PIM1 (0.81) | PIM1PIM3PIM2PDE4BPDE3A | |
| SCHEMBL14852113 | 0.79 | PIM1 (0.67) | PIM1PIM3PIM2MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |