Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.65 |
| ▸ | PIM3 | Q86V86 | 3/20 | 0.65 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.65 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.50 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.50 |
| ▸ | CLK1 | P49759 | 3/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.50 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | MYLK2 | Q9H1R3 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852182 | 0.80 | PIM1 (0.74) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852096 | 0.79 | PIM1 (1.00) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852094 | 0.77 | DRD2 (0.45) | KMT2AALDH1A1 | |
| SCHEMBL14852447 | 0.77 | PIM1 (0.85) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852501 | 0.76 | PIM1 (0.93) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852269 | 0.76 | PIM1 (0.80) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852187 | 0.75 | PIM1 (0.79) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852130 | 0.75 | PIM1 (0.82) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL14852461 | 0.75 | PIM1 (0.76) | PIM1PIM3PIM2DYRK1ADYRK2 | |
| SCHEMBL2880317 | 0.75 | PIK3CD (0.48) | PIM1PIM3PIM2DYRK1ADYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |