Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 3/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233274 | 0.91 | MAPT (0.61) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL14852052 | 0.86 | AKR1C3 (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL14852159 | 0.85 | AKR1C3 (0.46) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL20733001 | 0.84 | KMT2A (0.51) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL3490682 | 0.83 | MAPK1 (0.66) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL3494240 | 0.82 | AKR1C3 (0.57) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL14852208 | 0.80 | NPC1 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL2654792 | 0.80 | MAPT (0.54) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL25353287 | 0.79 | AKR1C3 (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL14852279 | 0.79 | AKR1C3 (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |