Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 4/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.43 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852201 | 0.85 | AKR1C4 (0.61) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 | |
| SCHEMBL14852282 | 0.79 | MAPT (0.46) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 | |
| SCHEMBL8233274 | 0.77 | MAPT (0.61) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 | |
| SCHEMBL18153017 | 0.76 | MAPT (0.48) | MAPTHPGDHCAR3MEN1KMT2A | |
| SCHEMBL14852054 | 0.76 | MAPT (0.55) | AKR1C3AKR1C2MAPTARMEN1 | |
| SCHEMBL14852150 | 0.75 | ALDH1A1 (0.54) | MAPTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4833667 | 0.75 | CASP6 (0.56) | MAPTHPGDHCAR3MEN1KMT2A | |
| SCHEMBL14852049 | 0.75 | CREBBP (0.40) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 | |
| SCHEMBL31144747 | 0.74 | AKR1C3 (0.52) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 | |
| SCHEMBL1668165 | 0.74 | HCAR3 (0.59) | AKR1C3AKR1C2MAPTAKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013051672-A1 | MEDICINAL AGENT COMPRISING THIAZOLIDINE DERIVATIVE OR SALT THEREOF AS ACTIVE INGREDIENT | 株式会社ヤクルト本社 (JP) | 2013-04-11 | — | — | WO | disclosed |