SCHEMBL14853286

SCHEMBL14853286

CC(=O)NCc1cnn(-c2ccccc2)n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.59
LSS P48449 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
HDAC1 Q13547 2/20 0.47
ELOVL1 Q9BW60 1/20 0.46
PDE10A Q9Y233 1/20 0.46
MALT1 Q9UDY8 1/20 0.44
ADORA2A P29274 2/20 0.44
KDM4E B2RXH2 2/20 0.42
MAPT P10636 1/20 0.42
USP7 Q93009 1/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
TSHR P16473 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10310331 0.79 P2RX7 (0.59) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL12146363 0.75 P2RX7 (0.68) P2RX7LSSNPSR1HDAC1ELOVL1
SCHEMBL14736048 0.75 P2RX7 (0.63) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL5294250 0.73 P2RX7 (0.59) P2RX7LSSELOVL1KDM4EALDH1A1
SCHEMBL1514733 0.72 P2RX7 (0.68) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL6399282 0.72 P2RX7 (0.68) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL29300000 0.72 NOTUM (0.66) NPC1
SCHEMBL9963336 0.71 P2RX7 (0.62) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL14736049 0.69 P2RX7 (0.64) P2RX7LSSHDAC1ELOVL1PDE10A
SCHEMBL32674134 0.69 MAPT (0.59) P2RX7HDAC1ADORA2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-9328205-B2 Iron(III) containing complex and condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-05-03 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
US-20140371056-A1 Iron(III) Containing Complex and Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW COMING CORPORATION (US) 2014-12-18 US disclosed
WO-2013052585-A2 IRON(III) CONTAINING COMPLEX AND CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-04-11 WO disclosed