Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15680418 | 0.78 | ADORA2A (0.54) | ADORA2AADORA2BMAPK8ESR1SRC | |
| SCHEMBL14854483 | 0.76 | BAZ2B (0.41) | ADORA2AADORA2BESR1SRCPOLB | |
| SCHEMBL15680239 | 0.69 | TP53 (0.40) | SRCKDM4EALDH1A1CYP3A4THRB | |
| SCHEMBL391398 | 0.67 | ADORA2A (0.39) | ADORA2AADORA2BMAPK8MAPK9PIM3 | |
| SCHEMBL15730578 | 0.67 | ESR1 (0.60) | ADORA2AADORA2BESR1PIM3PIM2 | |
| SCHEMBL19147139 | 0.67 | KDM4E (0.40) | SRCSPRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL14854366 | 0.64 | ESR1 (0.44) | ADORA2AADORA2BMAPK8MAPK9ESR1 | |
| SCHEMBL25300107 | 0.63 | HTT (0.43) | ADORA2AADORA2BMAPK8MAPK9SPR | |
| SCHEMBL29402024 | 0.63 | HTT (0.43) | ADORA2AADORA2BMAPK8MAPK9SPR | |
| SCHEMBL19426037 | 0.63 | SRC (0.44) | SRCKDM4EALDH1A1HPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052568-A1 | ANTIBACTERIAL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-04-11 | — | — | WO | disclosed |