Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SPR | P35270 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25300107 | 1.00 | HTT (0.43) | HTTLMNAPOLBSPRADORA2A | |
| SCHEMBL25256531 | 0.80 | MAPK1 (0.53) | HTTLMNAPOLBSPRMAPT | |
| SCHEMBL29405164 | 0.80 | MAPK1 (0.53) | HTTLMNAPOLBSPRMAPT | |
| SCHEMBL29404957 | 0.79 | KDM4E (0.42) | HTTLMNAPOLBGAATRPM4 | |
| SCHEMBL25256662 | 0.79 | KDM4E (0.42) | HTTLMNAPOLBGAATRPM4 | |
| SCHEMBL25260679 | 0.78 | CA9 (0.46) | HTTLMNAPOLBGAAMEN1 | |
| SCHEMBL29404883 | 0.78 | CA9 (0.46) | HTTLMNAPOLBGAAMEN1 | |
| SCHEMBL25302065 | 0.77 | ATM (0.49) | LMNAPOLBADORA2AADORA2BMAPT | |
| SCHEMBL29405109 | 0.77 | ATM (0.49) | LMNAPOLBADORA2AADORA2BMAPT | |
| SCHEMBL25294520 | 0.76 | KHK (0.46) | HTTLMNASPRGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115956071-A | Imidazoquinoline or benzindazolone compounds and intermediates for their preparation | LMITO药业株式会社 | 2023-04-11 | — | — | CN | disclosed |
| WO-2022039460-A1 | IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME | 주식회사 엘마이토테라퓨틱스 | 2022-02-24 | — | — | WO | disclosed |