Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 6/20 | 0.54 |
| ▸ | NISCH | Q9Y2I1 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.45 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14854515 | 0.97 | PRMT1 (0.54) | PRMT1NISCHGAATSHRPRMT3 | |
| SCHEMBL14854513 | 0.96 | PRMT1 (0.56) | PRMT1NISCHGAATSHRPRMT3 | |
| SCHEMBL14854585 | 0.85 | PRMT1 (0.44) | PRMT1NISCHGAATSHRPRMT3 | |
| SCHEMBL14854539 | 0.84 | PRMT1 (0.45) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854537 | 0.82 | PRMT1 (0.59) | PRMT1NISCHGAATSHRPRMT3 | |
| SCHEMBL10125964 | 0.80 | PRMT1 (0.63) | PRMT1NISCHPRMT3EHMT2PRMT6 | |
| SCHEMBL14854511 | 0.77 | PRMT1 (0.58) | PRMT1NISCHPRMT3EHMT2PRMT6 | |
| SCHEMBL14817007 | 0.76 | PRMT1 (0.55) | PRMT1NISCHPRMT3EHMT2PRMT6 | |
| SCHEMBL14854595 | 0.76 | PRMT1 (0.52) | PRMT1NISCHPRMT3EHMT2PRMT6 | |
| SCHEMBL31621369 | 0.75 | PRMT1 (0.57) | PRMT1NISCHPRMT3EHMT2PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052263-A2 | ANTIFUNGAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2013-04-11 | — | — | WO | disclosed |