SCHEMBL10125964

SCHEMBL10125964

CCc1cc2ccc(C3=NCCN3)cc2[nH]1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 6/20 0.63
▸ NISCH Q9Y2I1 7/20 0.57
▸ PRMT3 O60678 1/20 0.51
▸ EHMT2 Q96KQ7 1/20 0.51
▸ PRMT6 Q96LA8 1/20 0.51
▸ PRMT8 Q9NR22 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20198570 0.81 PRMT1 (0.68) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL8229714 0.81 PRMT1 (0.71) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL14854513 0.81 PRMT1 (0.56) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL8238119 0.80 PRMT1 (0.69) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL14854515 0.80 PRMT1 (0.54) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL14854514 0.80 PRMT1 (0.54) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL362453 0.78 PRMT1 (0.68) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL8235286 0.78 PRMT1 (0.63) PRMT1NISCHPRMT3EHMT2PRMT6
Hydrochloric Acid SCHEMBL3383477 0.77 PRMT1 (0.66) PRMT1NISCHPRMT3EHMT2PRMT6
SCHEMBL8235649 0.77 PRMT1 (1.00) PRMT1NISCHPRMT3EHMT2PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120035198-A1 Antiviral Compounds and Methods of Using Thereof AMAN MOHAMMAD JAVAD (US) 2012-02-09 — — US disclosed
US-20110086877-A1 Small Molecule Inhibitors of Botulinum Neurotoxins BAVARI SINA 2011-04-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035198-A1 Antiviral Compounds and Methods of Using Thereof ZC3HAV1, MAVS, ZC3HAV1L PRMT1 1610/4885NISCH 91/4885PRMT3 675/4885
US-20110086877-A1 Small Molecule Inhibitors of Botulinum Neurotoxins ACHE, MMP2, TIMP3 PRMT1 2768/4885NISCH 268/4885PRMT3 2069/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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