Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 4/20 | 0.88 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.88 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.88 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.88 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 2/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204583 | 0.93 | PRMT1 (1.00) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854546 | 0.92 | PRMT1 (0.74) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854531 | 0.86 | PRMT1 (0.65) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854565 | 0.85 | PRMT1 (0.64) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854564 | 0.83 | PRMT1 (0.62) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854537 | 0.83 | PRMT1 (0.59) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854590 | 0.82 | PRMT1 (0.60) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854511 | 0.81 | PRMT1 (0.58) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14817030 | 0.81 | PRMT1 (0.59) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854601 | 0.79 | PRMT1 (0.57) | PRMT1PRMT3EHMT2PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013052263-A2 | ANTIFUNGAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2013-04-11 | — | — | WO | disclosed |