Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 5/20 | 1.00 |
| ▸ | PRMT3 | O60678 | 1/20 | 1.00 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 1.00 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 1.00 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 1.00 |
| ▸ | NISCH | Q9Y2I1 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14854516 | 0.93 | PRMT1 (0.88) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854546 | 0.85 | PRMT1 (0.74) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854501 | 0.85 | PRMT1 (0.74) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14535010 | 0.83 | PRMT1 (0.70) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8238119 | 0.83 | PRMT1 (0.69) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14854553 | 0.82 | PRMT1 (0.69) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL362453 | 0.81 | PRMT1 (0.68) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL8229714 | 0.81 | PRMT1 (0.71) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| SCHEMBL14817020 | 0.80 | PRMT1 (0.67) | PRMT1PRMT3EHMT2PRMT6PRMT8 | |
| Hydrochloric Acid SCHEMBL3383477 | 0.80 | PRMT1 (0.66) | PRMT1PRMT3EHMT2PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |
| EP-1945209-B1 | BROAD SPECTRUM ANTIBACTERIAL COMPOUNDS | US GOV AS REPRESENTED BY THE SECRETARY OF THE UNITED STATES ARMY AND THE U S ARMY MEDICAL RESEARCH (US) | 2018-05-30 | — | — | EP | disclosed |
| US-7781183-B2 | Inhibition of anthrax lethal factor protease | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2010-08-24 | — | — | US | disclosed |
| US-7781183-B2 | Inhibition of anthrax lethal factor protease | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112048-A1 | Broad Spectrum Antibacterial Compounds | MPO, CAT, LPO | PRMT1 2817/4885PRMT3 2516/4885EHMT2 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.