SCHEMBL14855133

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2943166	0.86	EGFR (0.85)	EGFRGAKERBB2MAP2K1RAF1
	SCHEMBL14854719	0.85	EGFR (0.61)	EGFRGAKERBB2MAP2K1RAF1
	SCHEMBL30132269	0.84	EGFR (0.72)	EGFRGAKERBB2
	SCHEMBL2131741	0.84	EGFR (0.72)	EGFRGAKERBB2
	SCHEMBL29670932	0.84	EGFR (0.72)	EGFRGAKERBB2
	SCHEMBL14854974	0.84	MAP2K1 (0.69)	EGFRERBB2MAP2K1RAF1
	SCHEMBL14854972	0.84	MAP2K1 (0.49)	EGFRERBB2MAP2K1RAF1
	SCHEMBL3593063	0.82	EGFR (0.86)	EGFRGAKERBB2RAF1
	SCHEMBL14854808	0.81	MAP2K1 (0.58)	EGFRERBB2MAP2K1RAF1
	SCHEMBL14854822	0.81	SRC (0.51)	EGFRERBB2MAP2K1RAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.