Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.72 |
| ▸ | GAK | O14976 | 2/20 | 0.72 |
| ▸ | ERBB2 | P04626 | 12/20 | 0.69 |
| ▸ | STK4 | Q13043 | 4/20 | 0.56 |
| ▸ | FBP1 | P09467 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30132269 | 1.00 | EGFR (0.72) | EGFRGAKERBB2STK4FBP1 | |
| SCHEMBL2131741 | 1.00 | EGFR (0.72) | EGFRGAKERBB2STK4FBP1 | |
| SCHEMBL22419601 | 0.94 | EGFR (0.71) | EGFRGAKERBB2STK4SRC | |
| SCHEMBL2943166 | 0.90 | EGFR (0.85) | EGFRGAKERBB2SRC | |
| SCHEMBL3593063 | 0.90 | EGFR (0.86) | EGFRGAKERBB2SRC | |
| SCHEMBL20584416 | 0.87 | EGFR (0.71) | EGFRGAKERBB2STK4SRC | |
| SCHEMBL1897571 | 0.87 | EGFR (0.85) | EGFRGAKERBB2STK4 | |
| SCHEMBL29670935 | 0.85 | EGFR (0.67) | EGFRGAKERBB2STK4 | |
| SCHEMBL28487491 | 0.85 | EGFR (0.67) | EGFRGAKERBB2STK4 | |
| SCHEMBL14855133 | 0.84 | EGFR (0.66) | EGFRGAKERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111875539-B | Preparation method of EGFR (epidermal growth factor receptor) molecular targeted antitumor drug | 苏中药业集团股份有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-111875539-B | Preparation method of EGFR (epidermal growth factor receptor) molecular targeted antitumor drug | 苏中药业集团股份有限公司 | 2022-06-21 | — | — | CN | disclosed |