SCHEMBL14855243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14854665	0.87	MRGPRX4 (0.48)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL14854821	0.87	MRGPRX4 (0.55)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL13929749	0.86	MRGPRX4 (0.58)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL14854921	0.84	NPC1 (0.51)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL14855309	0.84	CCR5 (0.52)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL3320471	0.84	MAOB (0.56)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL31193398	0.84	MAOB (0.56)	MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
	SCHEMBL11091418	0.83	FFAR4 (0.48)	MRGPRX4NPC1RAB9ACYP3A4AGXT
	SCHEMBL632895	0.83	MRGPRX4 (0.57)	MRGPRX4NPC1RAB9ASMN1; SMN2MAPT
	SCHEMBL12173115	0.83	MRGPRX4 (0.58)	MRGPRX4NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.