Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 14/20 | 0.94 |
| ▸ | ADH1C | P00326 | 11/20 | 0.94 |
| ▸ | ADH4 | P08319 | 3/20 | 0.89 |
| ▸ | ADH1B | P00325 | 5/20 | 0.50 |
| ▸ | ADH7 | P40394 | 3/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913207 | 1.00 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10013014 | 1.00 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL39255 | 1.00 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL8745531 | 1.00 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10012570 | 1.00 | ADH1A (0.94) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL5122418 | 0.97 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL3160136 | 0.97 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| Cyclobutyl(Cyclopentyl)Formamide SCHEMBL4315833 | 0.97 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL6005197 | 0.94 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL4496323 | 0.94 | ADH1A (1.00) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | HORIKOSHI, HIROYOSHI (CA) | 2013-06-27 | — | — | US | disclosed |
| EP-2581373-A1 | BENZO- OR PYRIDO-IMIDAZOLE DERIVATIVE | Fujita, Takashi (JP) | 2013-04-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165446-A1 | BENZO-OR PYRIDO-IMIDAZOLE DERIVATIVE | PPARG, PPARA, PPARD | ADH1A 1349/4885ADH1C 1360/4885ADH4 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.