SCHEMBL14856641

SCHEMBL14856641

CCCCOC(=O)N1CCCC(C(OCCNC(=O)OC)c2cccc(Cl)c2)C1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.66
CYP3A4 P08684 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14856640 1.00 REN (0.66) RENCYP3A4
SCHEMBL4248149 0.90 REN (0.65) RENCYP3A4
SCHEMBL4968724 0.88 REN (0.56) RENCYP3A4
SCHEMBL4968733 0.88 REN (0.56) RENCYP3A4
SCHEMBL970786 0.87 REN (0.70) RENCYP3A4
SCHEMBL2996480 0.87 REN (0.70) RENCYP3A4
SCHEMBL2996483 0.87 REN (0.70) RENCYP3A4
SCHEMBL970785 0.87 REN (0.70) RENCYP3A4
SCHEMBL2996478 0.87 REN (0.70) RENCYP3A4
SCHEMBL968963 0.87 REN (0.68) RENCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2581366-A1 Renin Inhibitors Vitae Pharmaceuticals, Inc. (US) 2013-04-17 EP disclosed