SCHEMBL14857486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28562010	0.79	TSHR (0.47)	TSHRBRD4CYP17A1CYP19A1
	SCHEMBL14857830	0.79	TSHR (0.39)	TSHRBRD4CYP17A1CYP19A1HRH1
	Hydrochloric Acid SCHEMBL28561898	0.78	TSHR (0.46)	TSHRBRD4CYP17A1CYP19A1TDP1
	SCHEMBL14857787	0.77	ALDH1A1 (0.41)	TSHRBRD4CYP17A1CYP19A1
	SCHEMBL5674598	0.76	TAAR1 (0.47)	TSHRBRD4CYP19A1SLC6A2SLC6A4
	SCHEMBL27875013	0.76	TSHR (0.40)	TSHRCYP19A1KMT2ASLC6A2SLC6A4
	SCHEMBL730151	0.76	TSHR (0.44)	TSHRBRD4CYP17A1CYP19A1SLC6A2
	SCHEMBL14858160	0.75	HPGD (0.36)	—
	SCHEMBL732500	0.73	TSHR (0.41)	TSHRBRD4CYP17A1CYP19A1SLC6A2
	SCHEMBL27693133	0.72	BRD4 (0.40)	TSHRBRD4CYP19A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.