SCHEMBL1485752

SCHEMBL1485752

CCCCNc1ccc(C)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.70
HPGD P15428 2/20 0.46
HTT P42858 1/20 0.45
ALDH1A1 P00352 3/20 0.44
HRH3 Q9Y5N1 2/20 0.44
LMNA P02545 2/20 0.44
SCN5A Q14524 2/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
MAOA P21397 1/20 0.44
CNR1 P21554 1/20 0.44
DRD4 P21917 1/20 0.44
ACHE P22303 1/20 0.44
HRH2 P25021 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
NTSR1 P30989 1/20 0.44
HRH1 P35367 1/20 0.44
DRD3 P35462 1/20 0.44
SCN1A P35498 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2494993 0.94 MAPT (0.61) MAPTHPGDHTTALDH1A1HRH3
SCHEMBL2256877 0.93 MAPT (0.67) MAPTHTTALDH1A1HRH3PLK1
SCHEMBL29183022 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL29226064 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL11324887 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL3678588 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL11508663 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL11328551 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL3682494 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1
SCHEMBL11331977 0.91 MAPT (0.64) MAPTHTTPLK1ABL1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4360621-A FOR RUBBERS AND POLYURETHANES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-23 US claimed
US-3960749-A Liquid-crystal mixtures for use in liquid-crystal displays INTERNATIONAL LIQUID XTAL COMPANY (US) 1976-06-01 US claimed
EP-4694606-A1 RADIO WAVE SHIELDING BODY AND ADHESIVE COMPOSITION Zeon Corporation (JP) 2026-02-11 EP disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
WO-2024204796-A1 RADIO WAVE SHIELDING BODY AND ADHESIVE COMPOSITION 日本ゼオン株式会社 2024-10-03 WO disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
EP-4282934-A1 LIQUID-CRYSTAL COMPOSITION CONTAINING ANTHRAQUINONE COMPOUND AND LIGHT-MODULATING ELEMENT Nippon Kayaku Kabushiki Kaisha (JP) 2023-11-29 EP disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents WILLIAM MARSH RICE UNIVERSITY (US) 2023-09-26 US disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
US-4399285-A HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1983-08-16 US disclosed
US-4360621-A FOR RUBBERS AND POLYURETHANES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-11-23 US disclosed
US-4334073-A BASIC CATALYSTS, DEACETYLATION, ESTERIFICATION BAYER AKTIENGESELLSCHAFT (DE) 1982-06-08 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
EP-0002721-B1 PROCESS FOR PREPARING HYDRAZINES BAYER AG (DE) 1981-09-02 EP disclosed
EP-0002721-A2 Process for preparing hydrazines BAYER AG (DE) 1979-07-11 EP disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-4079012-A Synthetic ester oil compositions containing organic sulfonic acid ammonium salts as load-carrying agents BOSNIACK DAVID S 1978-03-14 US disclosed
US-3944670-A Pesticidal dithiazolium salts E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-03-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767291-B2 Preparation of secondary amines with electrophilic N-linchpin reagents PNMT, NCL, NPM1 MAPT 1551/4885HPGD 3275/4885HTT 771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.