SCHEMBL14859331

SCHEMBL14859331

CC12CC3(C)CC(Br)(C1)CC(CO)(C2)C3

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31599397 1.00
SCHEMBL4040646 0.85 PKM (0.36)
SCHEMBL4034941 0.83 PKM (0.35)
SCHEMBL29751151 0.83
SCHEMBL14932913 0.83
SCHEMBL20115811 0.80
SCHEMBL1939702 0.77 PKM (0.35)
SCHEMBL4038153 0.74 DPP4 (0.32)
SCHEMBL3386097 0.74 PKM (0.33)
SCHEMBL3336213 0.73 GRIN1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115972693-B Tipping-resistant metal ceramic cutter and preparation method thereof 江苏伊斯达尔精密科技有限公司 2024-01-05 CN claimed
CN-115972693-A Tipping-resistant metal ceramic cutter and preparation method thereof 江苏伊斯达尔精密科技有限公司 2023-04-18 CN claimed
EP-4717316-A2 ANTI-EGFR ANTIBODY-DRUG CONJUGATES AbbVie Inc. (US) 2026-04-01 EP disclosed
US-20250263491-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-08-21 US disclosed
US-20250213685-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2025-07-03 US disclosed
US-20250177374-A1 BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same ABBVIE INC (US) 2025-06-05 US disclosed
US-20250170263-A1 ANTI-EGFR ANTIBODY-DRUG CONJUGATES ABBVIE INC (US) 2025-05-29 US disclosed
US-20240285611-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2024-08-29 US disclosed
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
US-20240199745-A1 ANTI-EGFR ANTIBODY DRUG CONJUGATES ABBVIE INC (US) 2024-06-20 US disclosed
WO-2016094505-A1 ANTIBODY DRUG CONJUGATES WITH CELL PERMEABLE BCL-XL INHIBITORS ABBVIE INC. (US) 2016-06-16 WO disclosed
US-20160158218-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC (US) 2016-06-09 US disclosed
US-20160158377-A1 BCL-XL Inhibitory Compounds and Antibody Drug Conjugates Including the Same ABBVIE INC. (US) 2016-06-09 US disclosed
US-9227963-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. (US) 2016-01-05 US disclosed
US-9187472-B2 NAMPT inhibitors ABBVIE INC. (US) 2015-11-17 US disclosed
US-20150072978-A1 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC (US) 2015-03-12 US disclosed
US-8889675-B2 Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases ABBVIE INC. (US) 2014-11-18 US disclosed
US-20130303511-A1 NAMPT INHIBITORS ABBVIE INC. (US) 2013-11-14 US disclosed
US-20130096120-A1 APOPTOSIS-INDUCED AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2013-04-18 US disclosed