SCHEMBL1485995

SCHEMBL1485995

O=S(=O)(O)c1cccc2c(-c3c[nH]nn3)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.46
CYP1A2 P05177 4/20 0.38
MEN1 O00255 1/20 0.36
NSD2 O96028 1/20 0.36
POLB P06746 1/20 0.36
IDE P14735 1/20 0.36
DUSP3 P51452 1/20 0.36
CCR6 P51684 1/20 0.36
BLM P54132 1/20 0.36
KMT2A Q03164 1/20 0.36
COMT P21964 1/20 0.35
AURKA O14965 1/20 0.35
AURKB Q96GD4 1/20 0.35
SNCA P37840 2/20 0.34
CHAT P28329 1/20 0.34
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CDK2 P24941 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11407002 0.86 TTR (0.34) TTRMEN1BLMKMT2AALDH1A1
SCHEMBL15412668 0.81 KDM4E (0.32) TTRCYP1A2POLBBLMALDH1A1
SCHEMBL10632690 0.77 TDP1 (0.35) SUMO2SUMO1SENP7SENP2
SCHEMBL1485926 0.76 ALDH1A1 (0.38) CYP1A2MEN1BLMKMT2ASNCA
SCHEMBL29383992 0.76 TTR (0.67) TTRCYP1A2MEN1NSD2POLB
SCHEMBL1485875 0.74 ALDH1A1 (0.40) CYP1A2MEN1KMT2AALDH1A1HSD17B10
SCHEMBL30233642 0.74 TTR (0.75) TTRCYP1A2MEN1NSD2POLB
SCHEMBL29363198 0.74 TTR (0.75) TTRCYP1A2MEN1NSD2POLB
SCHEMBL6242 0.74 TTR (0.75) TTRCYP1A2MEN1NSD2POLB
SCHEMBL367742 0.74 NISCH (0.41) MEN1KMT2AALDH1A1ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2674461-B1 AZO COMPOUND, DYE-BASED POLARIZING FILM, AND POLARIZING PLATE NIPPON KAYAKU KK (JP) 2019-03-27 EP disclosed
US-20190048194-A1 Azo Compound Or Salt Thereof, And Polarizing Film Containing Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2019-02-14 US disclosed
EP-3421546-A1 AZO COMPOUND OR SALT THEREOF, AND POLARIZING FILM CONTAINING SAME Nippon Kayaku Kabushiki Kaisha (JP) 2019-01-02 EP disclosed
US-10150871-B2 Azo compound, dye-based polarizing film containing same, and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-12-11 US disclosed
US-20170210902-A1 Azo Compound, Dye-Based Polarizing Film Containing Same, And Polarizing Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-07-27 US disclosed
EP-3127965-A1 AZO COMPOUND, DYE-BASED POLARIZING FILM CONTAINING SAME, AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2017-02-08 EP disclosed
US-9354371-B2 Azo compounds, and dye-based polarizing films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-31 US disclosed
US-9341746-B2 Azo compound, dye-based polarizing film and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160109619-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate POLATECHNO CO LTD (JP) 2016-04-21 US disclosed
US-9244198-B2 Azo compound, dye-based polarizing film and polarizing plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150331148-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate NIPPON KAYAKU KK (JP) 2015-11-19 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed
EP-2752694-A1 POLARIZING ELEMENT AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2014-07-09 EP disclosed
EP-2674461-A1 AZO COMPOUND, DYE-BASED POLARIZING FILM, AND POLARIZING PLATE Nippon Kayaku Kabushiki Kaisha (JP) 2013-12-18 EP disclosed
US-20130302538-A1 Azo Compound, Dye-Based Polarizing Film And Polarizing Plate POLATECHNO CO., LTD. (JP) 2013-11-14 US disclosed
US-8477268-B2 Azo compound and salts thereof, as well as dye-based polarization films and polarizing plates comprising the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2013-07-02 US disclosed
US-20110164208-A1 Azo Compound And Salts Thereof, As Well As Dye-Based Polarization Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-07-07 US disclosed
US-20110075076-A1 Azo Compounds, And Dye-Based Polarizing Films And Polarizing Plates Comprising The Same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-03-31 US disclosed