SCHEMBL1486033

SCHEMBL1486033

C=C(C(N)=O)C(C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.42
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 1/20 0.36
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
LDHA P00338 1/20 0.33
LDHB P07195 1/20 0.33
GABRR1 P24046 2/20 0.32
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7187887 0.86 TDP1 (0.47) SLC7A5TDP1LMNAMAPTXBP1
SCHEMBL2990564 0.84 ALOX15 (0.34) SLC7A5TDP1GRIK1GRIK2GRM1
SCHEMBL6054550 0.81 TDP1 (0.43) SLC7A5TDP1LMNAMAPTXBP1
SCHEMBL164038 0.78 TP53 (0.40) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL2815802 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL2816691 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL17178420 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL20790181 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL28876765 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1
SCHEMBL28323732 0.76 TP53 (0.38) SLC7A5TP53LMNAMAPTXBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110366430-A Biocompatible and hydrophilic polymer conjugates for targeted delivery of agents 联邦科学和工业研究组织 2019-10-22 CN claimed
CN-110004717-A A kind of multifunctional terylene fabric and preparation method thereof 苏州大学 2019-07-12 CN claimed
US-20190119415-A1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2019-04-25 US claimed
EP-2310104-B1 MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-10-18 EP claimed
EP-2152405-B2 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2017-04-05 EP claimed
CN-102112191-B Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2014-07-30 CN claimed
US-8673988-B2 Graft copolymers for ion exchange chromatography MERCK PATENT GMBH (DE) 2014-03-18 US claimed
CN-101678318-B Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2013-09-25 CN claimed
EP-2152405-B1 GRAFT COPOLYMER FOR CATION-EXCHANGE CHROMATOGRAPHY MERCK PATENT GMBH (DE) 2012-10-17 EP claimed
CN-102112191-A Graft copolymers for ion exchange chromatography MERCK PATENT GMBH 2011-06-29 CN claimed
US-20110136925-A1 GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-06-09 US claimed
CN-101678318-A Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2010-03-24 CN claimed
EP-0476117-A1 THERMOREVERSIBLE HEAT-THICKENING POLYACRYLAMIDES. EASTMAN KODAK CO (US) 1992-03-25 EP claimed
US-12421380-B2 Acrylic copolymer and rubber material OSAKA SODA CO., LTD. (JP) 2025-09-23 US disclosed
US-12180311-B2 Method for producing acrylic rubber OSAKA SODA CO., LTD. (JP) 2024-12-31 US disclosed
US-20220185913-A1 METHOD FOR PRODUCING ACRYLIC RUBBER OSAKA SODA CO., LTD. (JP) 2022-06-16 US disclosed
CN-102046285-A Ce (IV) -initiated graft polymerization on polymers without hydroxyl groups MERCK PATENT GMBH 2011-05-04 CN disclosed
US-20110073547-A1 Ce(IV)-initiated graft polymerisation on polymers containing no hydroxyl groups MERCK PATENT GESELLSCHAFT (DE) 2011-03-31 US disclosed
US-20100181254-A1 GRAFT COPOLYMER FOR CATION- EXCHANGE CHROMATOGRAPHY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2010-07-22 US disclosed
CN-101678318-A Graft copolymer for cation-exchange chromatography MERCK PATENT GMBH 2010-03-24 CN disclosed