⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51994 | 1.00 | — | — | |
| SCHEMBL7879028 | 1.00 | — | — | |
| SCHEMBL1486297 | 1.00 | — | — | |
| SCHEMBL9033044 | 1.00 | — | — | |
| SCHEMBL8903050 | 0.93 | PRKCA (0.41) | — | |
| SCHEMBL7034989 | 0.93 | PRKCA (0.41) | — | |
| SCHEMBL51075 | 0.93 | PRKCA (0.41) | — | |
| SCHEMBL8903045 | 0.93 | PRKCA (0.41) | — | |
| SCHEMBL4980804 | 0.91 | PRKCA (0.44) | — | |
| SCHEMBL7343605 | 0.91 | PRKCA (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120197015-A1 | EPOXYCARBOXAMIDE COMPOUND, AZIDE COMPOUND, AND AMINO ALCOHOL COMPOUND, AND PROCESS FOR PREPARING a-KETO AMIDE COMPOUND USING THEM | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8163943-B2 | Epoxycarboxamide compound, azide compound, and amino alcohol compound, and process for preparing α-keto amide compound using them | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-2289888-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289888-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-2289887-A2 | Epoxycarboxylic acid amides, azides and amino alcohols and processes for preparation of alpha-keto amides by using them | SEIKAGAKU CORPORATION (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-20080064873-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-13 | — | — | US | disclosed |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-20080058516-A1 | Stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA D/B/A SEIKAGAKU CORPORATION (JP) | 2008-03-06 | — | — | US | disclosed |
| US-7326799-B2 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2008-02-05 | — | — | US | disclosed |
| US-7326799-B2 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2008-02-05 | — | — | US | disclosed |
| US-20030153788-A1 | Oxidizing an amino alcohol (obtained by ring opening the epoxy, aziding, reducing and reacting it with a carboxylic acid); stereoselectivity; protease inhibitors: antiallergens; anticarcinogenic and hypotensive agents | SEIKAGAKU CORPORATION (JP) | 2003-08-14 | — | — | US | disclosed |
| EP-1295876-A1 | EPOXYCARBOXYLIC ACID AMIDES, AZIDES AND AMINO ALCOHOLS AND PROCESSES FOR PREPARATION OF ALPHA-KETO AMIDES BY USING THEM | SEIKAGAKU CORPORATION (JP) | 2003-03-26 | — | — | EP | disclosed |
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |