SCHEMBL14864311

SCHEMBL14864311

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nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 1/20 0.34
▸ CYP2D6 P10635 1/20 0.32
▸ THRB P10828 1/20 0.32
▸ HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14864300 1.00 OGA (0.34) OGACYP2D6THRBHSD17B10
SCHEMBL17590143 1.00 OGA (0.34) OGACYP2D6THRBHSD17B10
SCHEMBL17590151 1.00 OGA (0.34) OGACYP2D6THRBHSD17B10
SCHEMBL18854300 0.89 OGA (0.38) OGACYP2D6THRBHSD17B10
SCHEMBL15267319 0.89 CYP2D6 (0.32) OGACYP2D6THRBHSD17B10
SCHEMBL18385935 0.86 CYP2D6 (0.43) CYP2D6THRBHSD17B10
SCHEMBL18589166 0.86 CYP2D6 (0.43) CYP2D6THRBHSD17B10
SCHEMBL15975741 0.86 CYP2D6 (0.43) CYP2D6THRBHSD17B10
SCHEMBL16367886 0.86 CYP2D6 (0.43) CYP2D6THRBHSD17B10
SCHEMBL18589293 0.86 CYP2D6 (0.43) CYP2D6THRBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987430-B2 Efficient and scalable process for the manufacture of fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2015-03-24 — — US disclosed
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-10-03 — — US disclosed
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-25 — — US disclosed
US-8420790-B2 Efficient and scalable process for the manufacture of Fondaparinux sodium RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2013-04-16 — — US disclosed
US-8288515-B2 Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-10-16 — — US disclosed
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2012-05-10 — — US disclosed
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2011-05-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105418-A1 PROCESS FOR PREPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF F11, TFPI, STS OGA 155/4885CYP2D6 1099/4885THRB 3708/4885
US-20130102764-A1 PROCESS FOR PERPARING FONDAPARINUX SODIUM AND INTERMEDIATES USEFUL IN THE SYNTHESIS THEREOF TFPI, PLG, PCSK6 OGA 129/4885CYP2D6 1479/4885THRB 3176/4885
US-20120116066-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 OGA 448/4885CYP2D6 1093/4885THRB 4515/4885
US-20130261291-A1 EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM F11, F10, F2 OGA 448/4885CYP2D6 1093/4885THRB 4515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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