SCHEMBL14864477

SCHEMBL14864477

COCC(=O)Nc1c(I)c(C(=O)NCC(O)COC)c(I)c(C(=O)N(C)CC(O)CO)c1I

nearest known ligand 0.91

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.91
CYP2C19 P33261 1/20 0.45
HIF1A Q16665 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iopromide SCHEMBL8845234 0.95 LMNA (1.00) LMNACYP2C19HIF1A
Iopromide SCHEMBL24546 0.95 LMNA (1.00) LMNACYP2C19HIF1A
Iopromide SCHEMBL29632300 0.95 LMNA (1.00) LMNACYP2C19HIF1A
SCHEMBL18931642 0.92 LMNA (0.91) LMNACYP2C19HIF1A
SCHEMBL13309814 0.92 LMNA (0.90) LMNACYP2C19HIF1A
SCHEMBL9009184 0.91 LMNA (0.93) LMNACYP2C19HIF1A
SCHEMBL12885826 0.89 LMNA (0.84) LMNACYP2C19HIF1A
SCHEMBL19505583 0.89 LMNA (0.87) LMNACYP2C19HIF1A
SCHEMBL13979309 0.88 LMNA (0.83) LMNACYP2C19HIF1A
SCHEMBL12885827 0.88 LMNA (0.79) LMNACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8420858-B2 Process for preparation of iopromide LG LIFE SCIENCES LTD. (KR) 2013-04-16 US disclosed